News: 2015

Merus Appoints Hui Liu as Chief Business Officer

December 18, 2015
Novartis Oncology's Former Global Head of Business Development and Licensing Joins Immuno-oncology Biotech Company UTRECHT, The Netherlands, Dec. 16, 2015 (GLOBE NEWSWIRE) - Merus B.V., a clinical-stage...
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Inthera Bioscience raises EUR 3.4 million in seed financing round

December 15, 2015
Zürich, Switzerland, December 14, 2015 - Inthera Bioscience, a Swiss biopharmaceutical company focused on the development of first-in-class targeted small molecule therapies for solid tumors, today announced...
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ISA Pharmaceuticals’ ISA101 Studied in Phase II Combination Trial with Checkpoint Inhibitor Nivolumab

December 07, 2015
• Trial in patients with HPV16-positive, incurable solid tumors initiated by MD Anderson Cancer Center in collaboration with ISA and Bristol-Myers Squibb Leiden, The Netherlands, December 7, 2015 - ISA Ph...
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InteRNA Technologies secures final extension Series A financing and strengthens its Supervisory Board

November 13, 2015
Nijmegen/Utrecht (the Netherlands) - InteRNA Technologies B.V., a  biopharma company engaged in the development of microRNA (miRNA)-based therapeutics for oncology, announces today the closing of an equity...
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Merus enters into 72.8 million euro series C financing led by Sofinnova Ventures and Novo A/S

August 27, 2015
UTRECHT, Netherlands, Aug. 26, 2015 - Merus B.V., a clinical-stage immuno-oncology company developing innovative bispecific antibody therapeutics, today announced that it has entered into an agreement with i...
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Aglaia is co-sponsoring Oncology Drug Development in Practice (ODDP) 2015

August 27, 2015
Aglaia is co-sponsoring the  Oncology Drug Development in Practice (ODDP) 2015 training course. The ODDP is a 3-day educational program, offered by Congress by design and INC Research, that teaches knowledge...
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Merus Prevails in Inequitable Conduct Case Against Regeneron

August 10, 2015
• Court ruling further strengthens Merus' freedom to operate in using transgenic mice for therapeutic human antibodies Utrecht, The Netherlands, August 10, 2015 -- Merus, a leader in developing best-in-clas...
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Towards a Best Practice Approach in Cancer Immunotherapy: Cancer Vaccines Gain Momentum

July 28, 2015
• Review in The Journal of Clinical Investigation points the way forward for therapeutic cancer vaccines Leiden, The Netherlands, July 28, 2015 - ISA Pharmaceuticals B.V., a clinical-stage immunotherapy com...
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ISA Pharmaceuticals Further Strengthens IP Position on Lead Compound ISA101

June 23, 2015
• Three additional European patents and market exclusivity granted for the use of key active ingredients of ISA101 Leiden, The Netherlands, June 23, 2015 - ISA Pharmaceuticals B.V., a clinical-stage immun...
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Merus appoints Mark Iwicki as President of the Supervisory Board

June 01, 2015
Utrecht, The Netherlands, June 1, 2015 -- Merus B.V., a leader in developing best-in-class bispecific antibody therapeutics to treat cancer patients, today announced that Mark Iwicki has been appointed as Pr...
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New Peer-Reviewed Publication Provides Further Insights into Mechanism of ISA Pharmaceuticals’ SLP® Immunotherapeutics

May 15, 2015
SLP®s modulate intratumoral macrophages required for tumor regression Leiden, The Netherlands, May 12, 2015 - ISA Pharmaceuticals B.V., a clinical-stage immunotherapy company focusing on rationally design...
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Successful product lead identification underscores the strength of Merus’ platform in delivering human, full-length IgG bispecific antibodies

April 08, 2015
Utrecht, The Netherlands, 8th April 2015 - Merus B.V., a leader in developing best-in-class bispecific antibody therapeutics, announced today that it has reached a preclinical milestone in a bispecific antib...
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ISA Pharmaceuticals Granted European Patent for the Intradermal Administration of ISA101

March 26, 2015
- Intradermal administration provides significant benefits compared to subcutaneous application - Leiden, The Netherlands, March 24, 2015 - ISA Pharmaceuticals B.V., a clinical-stage immunotherapy company...
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ISA Pharmaceuticals announces start of first Phase I/II clinical trial of its SLP®-AMPLIVANT® conjugates

March 02, 2015
• Leiden University Medical Center to study novel immunotherapeutic in HPV-positive head & neck cancer patients Leiden, The Netherlands, February 26, 2015 - ISA Pharmaceuticals B.V., a clinical-stage immu...
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Merus starts Phase I/II clinical trial for MCLA-128, an ADCC-enhanced bispecific antibody for solid tumors

February 06, 2015
- First patient dosed in trial with potent bispecific antibody overcoming resistance to HER2-targeted therapies - Utrecht, The Netherlands, February 4, 2015 -- Merus B.V., a leader in developing best-in-c...
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New Study Explains Synergy between Cancer Vaccine ISA101 and Chemotherapy

January 09, 2015
Tumor necrosis factor alpha (TNFα) produced by T cells following vaccination sensitizes tumor cells for eradication by certain chemotherapeutics Data published in Clinical Cancer Research support ongoing c...
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After US court ruling, Merus reaffirms freedom to operate for its MeMo® transgenic mouse for therapeutic human antibodies

January 06, 2015
- Regeneron's '018 patent' is considered invalid and Merus not infringing - Utrecht, The Netherlands, January 5, 2015 - Merus B.V., a leader in developing best-in-class antibody therapeutics to treat canc...
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Issuance of a new U.S. patent covering ORCA’s T1 oncolytic adenovirus technology

January 06, 2015
Nijmegen, The Netherlands - January 5th, 2015 - ORCA Therapeutics BV, a pioneer in the development of innovative oncolytic immunotherapies for treatment of cancer, announced today that it has secured key int...
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