About Aglaia

Aglaia invests in oncology drug development companies. Aglaia has a proven ability to select and mature early-stage breakthrough inventions that have the potential to transform cancer treatment.

Decades of experience

The Aglaia team has decades of experience in cancer research and oncology drug development Over the last 14 years, Aglaia has built an excellent reputation in starting up biotech companies that focus on oncology drug development.
Aglaia is committed to define the strategic directions of the companies it invests in in close collaboration with innovators and entrepreneurs. Aglaia brings hands-on experience in designing research and development plans, ranging from early screening and animal feasibility studies through clinical studies.

Aglaia Oncology Funds

  • Aglaia Oncology Fund I: dissolved
  • Aglaia Oncology Fund II: active
  • Aglaia Oncology Fund III: planned

Through its Oncology Funds I and II, Aglaia has invested in 12 early stage companies, of which 6 were founded by Aglaia. The experienced team has been involved in the development of more than 100 oncology products, The continuous strategic and operational involvement of the team with portfolio companies has contributed to a marked success rate in transitioning early-stage portfolio companies to clinical-stage companies. By doing so, Aglaia has de-risked and matured these companies up to the level at which they become attractive candidates for licensing, acquisition or IPO.

Goddess Aglaia

Goddess Aglaia

Aglaia was the Greek goddess of beauty and good health. Together with her two sisters (Thalia and Euphrosyne), she was one of the three graces. The three graces were regarded as the inspirers of culture, love and wisdom. Or, more in general, bringing the feeling of wellbeing to the people. In line with the three graces, it is the intention of Aglaia Oncology Funds to contribute to the good health and the wellbeing of people by developing innovative therapies for cancer with higher cure rates and less side effects.

Advisory Board

Alan Barge, Senior Vice President at ASLAN Pharmaceuticals and Chief Medical Officer at Carrick Therapeutics. Dr. Barge was trained in medicine at Oxford and London, and specialised in haematology and oncology. As former VP Oncology and Infection at AstraZeneca, Dr. Barge has great oncology drug development experience. Before joining AstraZeneca, Dr. Barge spent 8 years at Amgen as European Medical Director.

Gabriele Dallmann, Founder of Biopharma Excellence, EUCRAF and Pharmatching.com. Dr. Dallmann has over 25 years of experience in facilitating drug development and is an expert in the field of Regulatory Affairs, having worked amongst others at Committees of the European Medicines Agency (EMA) and at the German Paul-Ehrlich-Institut. Dr.Dallmann is biologist by training with a PhD in immunology from Berlin University (Charité).

 

Kees Melief, Prof. Melief is CSO of ISA Pharmaceuticals in Leiden, The Netherlands. Before becoming CSO of ISA, Prof. Kees Melief was Head of the Department Immunohematology and Bloodbank of the University Hospital in Leiden and Professor of Internal Medicine. Prof. Melief is a board member and advisor of multiple organizations and companies and is considered one of the world’s most renown tumor immunologists.

Herman Spolders,  (co)-founder of companies like Oncomethylome, Pluriomics and NCardia. He has 40 years of experience in the pharmaceutical and biotech industry in Europe and the U.S. He served on multiple boards and in various executive positions. Throughout his career, Herman Spolders has been instrumental in starting and growing biotech companies, IPO’s, forging large pharma-biotech collaborations, defining new product opportunities with a focus on clinical diagnostics for cancer or infectious diseases. He studied biochemistry at the University of Amsterdam and graduated at INSEAD.

Investments

Current Investments

Exited Portfolio Companies

Investment Criteria

 

Aglaia is looking for excellent cancer research with the potential to be translated into cancer medicines. This translates specifically in:

  • Early-stage oncology drug development
  • Disruptive science with the potential to transform cancer diagnosis and therapy
  • Spread across different drug modalities (small molecules, biologicals, etc.) and drug development phases (from target discovery up to clinical development)

Inventions should have a potential to be superior to standard of care treatment at time of market introduction and should lead to clear benefits for cancer patients and society.  Inventions should be preferably platform technologies but highly interesting drug candidates with first in class potential are also considered. Drug candidates must be rigorously validated in relevant and predictive preclinical cancer models. Evidence must be provided that inventions can be patented. 

Careers

Aglaia Oncology Funds combines its focus on oncology with disciplined financing and a hands-on involvement – up to the level of strategic and operational management – to ensure focus on value creation and capital efficiency: keys to success for early stage companies. New additions to our team should bring complimentary scientific as well as clinical, legal, financial and business development expertise to the company.

If you are interested, please send us your details and a CV to info@aglaia-oncology.com.

  Teamwork

Impact

Aglaia’s team and their limited partners are committed in achieving a positive impact on patents and society in addition to achieving a compelling financial return. Aglaia’s vision is that when stellar science is translated into great medicines for cancer patients, financial awards for those involved in this process will ultimately follow. In line with this philosophy, Aglaia has developed a tool to monitor the socio-economic impact of its investments in oncology biotech companies. Aglaia teamed up with the social impact consultancy firm Sinzer, now an affiliate of Grant Thornton, to jointly develop the first social impact measurement and management tool for the life sciences industry, using Sinzer’s existing web-based software for evaluation of social impact. The joint development of a framework specifically for the life sciences industry, called Aglaia Biomedical Impact Suite (ABIS), was completed in 2015.

With ABIS the socio-economic performance of the fund, portfolio companies and individual projects can be evaluated and consolidated in social impact reports. Over the last three years, Aglaia has used ABIS to collect social impact data from Aglaia Oncology Fund II (AOF II)’s portfolio companies. 800 cancer patients have been treated  so far with investigational drugs developed by AOFI and AOFII portfolio companies. AOFII’s portfolio companies collectively have more than 100 approved patents, 110 accepted scientific papers and more than 70 research collaborations, which illustrates the science-driven mentality and innovation ability. The AOFII companies collectively employs more than 100 FTEs and have outsourced close to 70 projects, thereby contributing to the  economy in the EU.  

It is the ambition of Aglaia and Sinzer/Grant Thornton to make this social impact platform broadly available to the life sciences community, thereby fostering socio-economics ethics and a patient-centric culture in this industry.

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