News: 2021
Modeling ischemic stroke in a triculture neurovascular unit on-a-chip
December 15, 2021
Scientists from MIMETAS introduce a new neurovascular unit on-a-chip model to study ischemic events in the human brain.
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Merus Presents Updated Analysis of Zenocutuzumab, Trastuzumab, and Vinorelbine in Patients with HER2+ Metastatic Breast Cancer at the San Antonio Breast Cancer Symposium
December 10, 2021
- The primary endpoint of Clinical Benefit Rate at 24 weeks with the triplet combination was met
- The triplet combination sho...
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InteRNA Technologies Announces U.S. FDA Clearance of IND Application for Phase I Clinical Trial with Lead microRNA Candidate INT-1B3 in Patients with Advanced Solid Tumors
December 02, 2021
IND approval enables clinical trial advancement and enrollment of
dose expansion cohorts in the US
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InteRNA Technologies Establishes Clinical Advisory Board and Appoints New Members to Scientific Advisory Board
October 19, 2021
-- Adding deep preclinical and clinical immuno-oncology expertise to expand InteRNA's preclinical pipeline and accelerate clini...
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InteRNA Appoints Established Oncology Innovator Andrea van Elsas, PhD, to its Supervisory Board
October 12, 2021
Appointment of Andrea van Elsas as a new member of the Company's Supervisory Board.
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Sapreme Boosts Development of its Endosomal Escape Technology Platform and Proprietary Pipeline with EUR 15M Series A
October 07, 2021
Sapreme Boosts Development of its Endosomal Escape Technology Platform and Proprietary Pipeline with EUR 15M Series A
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Merus Presents Early Clinical Data on MCLA-158 and Preclinical Data on Zenocutuzumab at the AACR-NCI-EORTC Virtual International Conference on Molecular Targets and Cancer Therapeutics
October 07, 2021
- Tumor shrinkage and partial responses observed in patients with advanced head and neck squamous cell carcinoma (HNSCC) treate...
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Sapreme Presents Promising New Preclinical Data at 17th Annual Meeting of Oligonucleotide Therapeutics Society
September 27, 2021
Sapreme Presents Promising New Preclinical Data at 17th Annual Meeting of Oligonucleotide Therapeutics Society
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ISA Pharmaceuticals Receives Fast Track Designation for Lead Product ISA101b
September 14, 2021
Fast Track designation for the treatment of recurrent and metastatic HPV16-positive oropharyngeal cancer to improve survival an...
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ORCA Therapeutics B.V. to Start Repeat-Dosing in Phase 1/2a Study of ORCA-010 in TreatmentNaïve Prostate Cancer Patients.
September 07, 2021
ORCA Therapeutics B.V. is pleased to announce the successful completion of the single-dose escalation cohorts of the Phase I/II...
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Stepping to the Exit - Publication in Nature Biotechnology
August 27, 2021
Building a business. Stepping to the exit.
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A Microfluidic 3D Endothelium-on-a-Chip Model to Study Transendothelial Migration of T Cells in Health and Disease
August 02, 2021
Scientists from MIMETAS and Merck introduce an assay to study 3D T cell dynamics under flow and in real-time using a high-throu...
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ISA, in partnership with Erasmus MC, is awarded TKI grant and expands clinical pipeline
July 20, 2021
Grant accelerates clinical development of immunotherapy to treat chronic hepatitis B virus infection
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ISA Pharmaceuticals announces successful closing of EUR 26 million funding round
July 13, 2021
The proceeds of this round will be used to advance the lead product ISA101b towards first marketing authorization as well as to...
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MIMETAS and Roche enter into a collaboration to develop human disease models for drug development
July 06, 2021
- Risk-sharing alliance on tailor-made phenotypic models for IBD and HBV
- Upfront payment and milestone payments for MIMETAS...
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Sapreme will present data at the RNAi-Based Therapeutics Summit, demonstrating the potential of its Endosomal Escape Enhancing compound SPT001 to enable superior targeted delivery of oligonucleotides.
June 10, 2021
Sapreme will present data at the RNAi-Based Therapeutics Summit, demonstrating the potential of its Endosomal Escape Enhancing...
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MIMETAS wins Deshima award for Dutch-Japanese business relations
June 07, 2021
MIMETAS wins Deshima award for Dutch-Japanese business relations.
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Merus Presents Clinical Data on Zenocutuzumab in NRG1-fusion (NRG1+) Cancers at the American Society of Clinical Oncology (ASCO) 2021 Annual Meeting (Oral Abstract)
June 04, 2021
- 61 patients with NRG1+ cancer have been enrolled, including 45 patients evaluable for response as of the April 13, 2021 data...
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Macrophage Pharma Appoints Dr Venkat Reddy as Chief Executive Officer
June 01, 2021
Macrophage Pharma Limited ('MPL') announced today that its Chief Scientific Officer (CSO), Dr Venkat Reddy PhD, has been appoin...
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MIMETAS Opens Phenotypic Screening Center
May 27, 2021
Largest reported organ-on-a-chip screen ever performed on a 3D angiogenesis assay
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