News

ISA Pharmaceuticals obtains broad patent protection in the US for proprietary AMPLIVANT® platform and compounds

April 21, 2016
- Granted US patent provides market exclusivity until 2032 - Leiden, The Netherlands, April 19, 2016 - ISA Pharmaceuticals B.V., a clinical-stage immunotherapy company focusing on rationally designed immu...
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Merus to Present Interim Clinical Data from Ongoing Phase 1/2 Clinical Trial of its Lead Bispecific Antibody Candidate, MCLA-128, at the American Association for Cancer Research 2016 Annual Meeting

April 18, 2016
Posted on 18 April, 2016 MCLA-128 Shows Favorable Safety Profile and Early Signs of Anti-Tumor Activity in Patients with Advanced Solid Tumors UTRECHT, The Netherlands, April 15, 2016 (GLOBE NEWSWIRE)...
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ISA Pharmaceuticals' Lead Product ISA101 Efficiently Engages the Immune System Against Virus-Induced Pre-malignant and Malignant Lesions

April 15, 2016
• ISA101 clinically effective against HPV-induced vulvar / vaginal lesions and cervical cancer • Optimum immunotherapy window in cancer identified Leiden, The Netherlands, April 14, 2016 - ISA Pharmaceu...
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ORCA Therapeutics raises €1.5 million for funding non clinical evaluation and GMP production of their lead product ORCA-010

April 01, 2016
NIJMEGEN, 01 - 04 - 2016 ORCA Therapeutics B.V. raises € 1.5 Million for the non clinical evaluation and GMP production of t...
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ORCA Therapeutics raises €1.5 million for funding non clinical evaluation and GMP production of their lead product ORCA-010

Scientific Review Endorses ISA Pharmaceuticals’ Strategy to Overcome Immune Evasion in Cancer Immunotherapy

March 11, 2016
- Targeting and Activating Dendritic Cells is the Key to Success Leiden, The Netherlands, March 11, 2016 - ISA Pharmaceuticals B.V., a clinical-stage immunotherapy company, has announced the publication o...
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Merus Announces Issuance of Three U.S. Patents Strengthening its Biclonics® Technology Platform for the Discovery and Manufacturing of Human Bispecific Antibodies

March 10, 2016
Utrecht, The Netherlands, March 9, 2016 -- Merus B.V., a clinical-stage immuno-oncology company developing innovative bispecific antibody therapeutics, announced today that the United States Patent and Tradem...
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Merus and Gustave Roussy Form Strategic Collaboration to Develop Innovative Bispecific Antibodies for Therapeutic Immuno-Oncology Applications

January 05, 2016
UTRECHT, The Netherlands and VILLEJUIF, France, Jan. 04, 2016 (GLOBE NEWSWIRE) -- Merus B.V., a clinical-stage immuno-oncology company developing innovative bispecific antibody therapeutics, and Institut Gus...
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ISA Pharmaceuticals Appoints Gerben Moolhuizen as Chief Business Development Officer

January 05, 2016
•    Seasoned executive brings over twenty years of commercial biotech and pharma experience Leiden, The Netherlands, January 5, 2016 - ISA Pharmaceuticals B.V., a clinical-stage immunotherapy company foc...
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Merus Appoints Hui Liu as Chief Business Officer

December 18, 2015
Novartis Oncology's Former Global Head of Business Development and Licensing Joins Immuno-oncology Biotech Company UTRECHT, The Netherlands, Dec. 16, 2015 (GLOBE NEWSWIRE) - Merus B.V., a clinical-stage...
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Inthera Bioscience raises EUR 3.4 million in seed financing round

December 15, 2015
Zürich, Switzerland, December 14, 2015 - Inthera Bioscience, a Swiss biopharmaceutical company focused on the development of first-in-class targeted small molecule therapies for solid tumors, today announced...
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ISA Pharmaceuticals’ ISA101 Studied in Phase II Combination Trial with Checkpoint Inhibitor Nivolumab

December 07, 2015
• Trial in patients with HPV16-positive, incurable solid tumors initiated by MD Anderson Cancer Center in collaboration with ISA and Bristol-Myers Squibb Leiden, The Netherlands, December 7, 2015 - ISA Ph...
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InteRNA Technologies secures final extension Series A financing and strengthens its Supervisory Board

November 13, 2015
Nijmegen/Utrecht (the Netherlands) - InteRNA Technologies B.V., a  biopharma company engaged in the development of microRNA (miRNA)-based therapeutics for oncology, announces today the closing of an equity...
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Aglaia is co-sponsoring Oncology Drug Development in Practice (ODDP) 2015

August 27, 2015
Aglaia is co-sponsoring the  Oncology Drug Development in Practice (ODDP) 2015 training course. The ODDP is a 3-day educational program, offered by Congress by design and INC Research, that teaches knowledge...
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Merus enters into 72.8 million euro series C financing led by Sofinnova Ventures and Novo A/S

August 27, 2015
UTRECHT, Netherlands, Aug. 26, 2015 - Merus B.V., a clinical-stage immuno-oncology company developing innovative bispecific antibody therapeutics, today announced that it has entered into an agreement with i...
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Merus Prevails in Inequitable Conduct Case Against Regeneron

August 10, 2015
• Court ruling further strengthens Merus' freedom to operate in using transgenic mice for therapeutic human antibodies Utrecht, The Netherlands, August 10, 2015 -- Merus, a leader in developing best-in-clas...
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Towards a Best Practice Approach in Cancer Immunotherapy: Cancer Vaccines Gain Momentum

July 28, 2015
• Review in The Journal of Clinical Investigation points the way forward for therapeutic cancer vaccines Leiden, The Netherlands, July 28, 2015 - ISA Pharmaceuticals B.V., a clinical-stage immunotherapy com...
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ISA Pharmaceuticals Further Strengthens IP Position on Lead Compound ISA101

June 23, 2015
• Three additional European patents and market exclusivity granted for the use of key active ingredients of ISA101 Leiden, The Netherlands, June 23, 2015 - ISA Pharmaceuticals B.V., a clinical-stage immun...
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Merus appoints Mark Iwicki as President of the Supervisory Board

June 01, 2015
Utrecht, The Netherlands, June 1, 2015 -- Merus B.V., a leader in developing best-in-class bispecific antibody therapeutics to treat cancer patients, today announced that Mark Iwicki has been appointed as Pr...
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New Peer-Reviewed Publication Provides Further Insights into Mechanism of ISA Pharmaceuticals’ SLP® Immunotherapeutics

May 15, 2015
SLP®s modulate intratumoral macrophages required for tumor regression Leiden, The Netherlands, May 12, 2015 - ISA Pharmaceuticals B.V., a clinical-stage immunotherapy company focusing on rationally design...
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Successful product lead identification underscores the strength of Merus’ platform in delivering human, full-length IgG bispecific antibodies

April 08, 2015
Utrecht, The Netherlands, 8th April 2015 - Merus B.V., a leader in developing best-in-class bispecific antibody therapeutics, announced today that it has reached a preclinical milestone in a bispecific antib...
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